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ZanaflexZanaflex (generic name Tizanidine) is a stronger muscle relaxer with more of a tendency to cause drowsiness.
Zanaflex relaxes the tense, rigid muscles caused by spasticity. It is prescribed for people with multiple sclerosis, spinal cord injuries, and other disorders that produce protracted muscles spasms. The effect of the drug peaks 1 to 2 hours after each dose and is gone within 3 to 6 hours, so it's best to schedule doses for shortly before the daily activities when relief of spasticity is most important.
Cautions: Zanaflex causes drowsiness in almost half the people who use it. It also tends to reduce blood pressure in many people, frequently leading to dizziness and light-headedness. The likelihood of significant drowsiness increases when Zanaflex is combined with other spasticity drugs, such as Lioresal, Klonopin, and Valium. When taking Zanaflex, always be cautious about driving or operating dangerous machinery.
Side Effects: Abnormal movements, blurred vision, constipation, dizziness, drowsiness, dry mouth, flu-like symptoms, frequent urination, low blood pressure, nervousness, runny nose, slow heartbeat, sore throat, speech disorders, urinary and other infections, vomiting, weakness or fatigue.
Interactions: Oral contraceptives tend to boost the amount of Zanaflex in the system. If you are using an oral contraceptive, you'll probably need a smaller dose of this drug.
Alcohol, or any drug that slows the nervous system (including other drugs taken for spasticity), increases the likelihood of drowsiness when taken with Zanaflex.