The World of
Chronic Pain

More than 125 million Amercians are suffering.

Diseases &

These conditions can cause a world of pain.

& Treatment

Be sure you know the cautions and side effects.

Help &

Finding help is not always simple for those in pain.

Safety &

These tips can help prevent a lifetime of pain.

News &

Up-to-date news on pain-related issues.


Percocet is also known as Endocet, Roxicet, Tylox. It contains two drugs -- acetaminophen and oxycodone. Acetaminophen is used to reduce both pain and fever. Oxycodone, a narcotic analgesic, is used for its calming effect and for pain. See information on oxycodone above.

Cautions: Even if taken only as prescribed, Percocet can lead quickly to physical and psychological dependence.

Side Effects: Dizziness, light-headedness, nausea, sedation, vomiting, which may be alleviated by lying down. Less common or rare side effects may include: constipation, depressed feeling, exaggerated feeling of well-being, itchy skin, skin rash, slowed breathing (at higher doses).

Interactions: Alcohol may increase the sedative effects of Percocet. You should not take Percocet with alcohol.

If Percocet is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Percocet with the following: antispasmodic drugs such as Cogentin, Bentyl, and Donnatal; major tranquilizers such as Thorazine and Mellaril; other narcotic painkillers such as Darvon and Demerol; sedatives such as Phenobarbital and Seconal; tranquilizers such as Xanax and Valium.